Developing, validating and clinically testing specific biomarkers, in order to support public h[]

Organisation/Company: Università Campus Bio-Medico di Roma Research Field: Engineering Researcher Profile: Recognised Researcher (R2), Leading Researcher (R4), First Stage Researcher (R1), Established Researcher (R3) Country: Italy Application Deadline: 10 Apr 2025 - 23:59 (UTC) Type of Contract: Temporary Job Status: Full-time Hours Per Week: 350 Offer Starting Date: 1 Jan 1970 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No Offer Description The research program aims at developing, validating and clinically testing innovative point-of-care (PoC) and/or invitro-diagnostic medical devices (IVMD), in order to support public health at a global level, with a particular focus on regulatory sciences for medical devices and digital health. In line with ongoing research projects, the candidate will focus on AI-enhanced detection of biomarkers for communicable (e.g., Ebola Virus Disease, MPOX disease) and non-communicable diseases, spanning from chronic cardiovascular diseases (e.g., cardiac amyloidosis, congestive heart failure), eye disease (e.g., inherited maculopathies, diabetic retinopathies), metabolic disease (e.g., diabetes) and rare cancers. The program includes five phases, which will be developed in parallel: Systematic review of the literature, aimed at consolidating the program itself and defining quantitative key performance indicators (KPIs). Design of trials aimed at acquiring primary and secondary data for the training, testing and evaluation of PoC and IVMD. Demonstrate and quantify the impact (safety, efficacy, cost-effectiveness, acceptability) of these models on diagnostic and therapeutic workflows, with particular attention to rare diseases and comorbidities. Study the possibility of integrating these models in the context of telemedicine programmes for screening, referral, early diagnosis, and post-therapeutic follow-up, also with Health Technology Assessment (HTA) methods and tools. Study of the acceptability and the sustainability of these models considering different perspectives (e.g., patient, doctors), policymakers (e.g., appraisal and pricing) and regulatory bodies (e.g., GDPR; CE marking of medical devices based on AI; how to draft and manage the technical file for the CE marking of these devices). The candidate will work with a multidisciplinary team of experts within the European and National projects running in the Research Unit of Intelligent Technologies for Health and Wellness, in which (s)he will be based. J-18808-Ljbffr

Location: provincia-di-roma, IT

Posted Date: 3/17/2025